Like most new medications, dosage recommendations for cannabis medicines are best established according to existing scientific research, careful integration of high-quality anecdotal evidence, and incorporation of individual patient outcomes. Finding the correct dose will be different for each patient, determined through a titration process guided by their physician. As more patients join the program and the knowledge base for physicians grows, prescribers will gain a better understanding of efficacy and how patients tolerate medical cannabis treatment.
The most important consideration in dosage and administration is to start at a very low dose and increase the dose slowly to determine the optimal efficacy while minimizing side effects. People with no prior experience using cannabis medicine should be especially careful to follow this guidance.
DR. KAREN KEOUGH, Pediatric Neurologist & Epileptologist
Chief Medical Officer, Compassionate Cultivation
Primary Medical Ingredient
CBD
Dosage Strengths
100 mg CBD & 5 mg THC per mL
Available Sizes
15 mL (1500 mg CBD)
30 mL (3000 mg CBD)
For Patients Over 50kg
For Patients Under 50kg
Primary Medical Ingredient
THC
Dosage Strengths
15 mg CBD & 5 mg THC per mL
Available Sizes
30 mL (450 mg CBD + 150 mg THC)
For Patients Over 50kg
For Patients 20 – 50kg
For Patients 10 – 20 kg
Primary Medical Ingredient
THC
Dosage Strengths
10 mg CBD & 10 mg THC per mL
Available Sizes
30 mL (300 mg CBD + 300 mg THC)
For Patients Over 50kg
For Patients 20 – 50kg
For Patients 10 – 20 kg
• For patients with anxiety, consider starting with 3:1 formulation (15mg CBD/mL) to gauge tolerance of THC.
Tinctures, sprays & lozenges are intended to be sublingual. A prescribed dose of the medication should be placed inside the mouth between the cheek and gums or under the tongue and allowed to be absorbed. The patient will usually feel an effect within 1-2 hours and the effect will usually last 4-6 hours, or longer. Medical cannabis can sometimes have a “biphasic effect,” where at low doses there may be one effect (wakefulness) and at higher doses the opposite effect (sleepiness). This is why titration is so important.
DOSING (mg CBD) |
DOSING (mL) |
---|---|
5 | 0.05 |
10 | 0.10 |
15 | 0.15 |
20 | 0.20 |
25 | 0.25 |
50 | 0.50 |
75 | 0.75 |
100 | 1.0 |
DOSING (mL) |
DOSING (mg CBD) |
DOSING (mg THC) |
---|---|---|
0.1 | 1.5 | 0.5 |
0.3 | 4.5 | 1.5 |
0.5 | 7.5 | 2.5 |
0.7 | 10.5 | 3.5 |
0.9 | 13.5 | 4.5 |
1.0 | 15 | 5 |
DOSING (mL) |
DOSING (mg CBD) |
DOSING (mg THC) |
---|---|---|
0.1 | 1 | 1 |
0.5 | 5 | 5 |
1.0 | 10 | 10 |
1.5 | 15 | 15 |
2.0 | 20 | 20 |
2.5 | 25 | 25 |